The proteomic analysis of oral bacterial pathogens

  • Head of Laboratory Professor Eric Reynolds

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    03 9341 1547

  • Project Details

    This project focuses on using using 2D-gel electrophoresis, multidimensional LC and mass spectrometry analyses to identify outer membrane associated proteins and antigens of Porphyromonas gingivalisTreponema denticola and Tanerella forsythia, the bacteria associated with periodontitis. We are also investigating the effect of environmental conditions including growth as a biofilm and iron availability on bacterial protein expression. This work will enable us not only to identify novel antigenic proteins that may be used for the development of vaccines against these bacteria but will also help us to understand the role of a variety of bacterial proteins in their virulence and physiology.

    Research Group

    Oral Biology Research Group

    Faculty Research Themes

    Infection and Immunology

    School Research Themes

    Oral Infection and Immunity

    Key Contact

    For further information about this research, please contact the research group leader.

    Department / Centre

    Melbourne Dental School

    Unit / Centre

    Oral Biology Research Group

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