The development of novel antimicrobial peptides from biological sources

Project Details

We have recently isolated and characterised a novel antimicrobial peptide from casein. This peptide is active against a range of oral bacteria and has little similarity with known antimicrobial peptides. We are currently investigating the mechanism of action of this peptide and have synthesized and tested the 21 residue phosphorylated peptide corresponding to the active region. The three dimensional structure of the peptide is currently under investigation using 2-D NMR. We are also bioprospecting for further novel bioactive peptides using a range of novel approaches.

Research Group

The Oral Microbiology and Microbiome Group

Faculty Research Themes

Infection and Immunology

School Research Themes

Oral Infection and Immunity

Key Contact

For further information about this research, please contact the research group leader.

Department / Centre

Melbourne Dental School

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