Oral Infection and Immunity

Focused on the understanding of oral diseases at the microbial, molecular & immunological level - with a view to the development of novel, effective, and specific prevention & treatment strategies

Groups / Projects	Research Lead	Dept / Centre
Antimicrobial materials – synthesis of novel peptides, nanoparticles and organic polymers to targeting antibiotic resistance in bacteria	Prof Neil O'Brien-Simpson	Melbourne Dental School
Assessment and prevention of erosion	Head of Laboratory Professor David Manton	Melbourne Dental School
Bacterial chemotaxis and chronic disease	Prof Stuart Dashper	Melbourne Dental School
Caries Detection and Diagnosis	Head of Laboratory Professor David Manton	Melbourne Dental School
Characterisation of biomineralising peptides and proteins	Head of Laboratory Professor Eric Reynolds	Melbourne Dental School
Characterisation of novel P. gingivalis cell surface proteinase/adhesins	Head of Laboratory Professor Eric Reynolds	Melbourne Dental School
Characterisation of potential virulence factors secreted by the type 9 secretion system of Porphyromonas gingivalis	Dr Michelle Glew	Melbourne Dental School
Development of periodontal disease vaccines	Head of Laboratory Professor Eric Reynolds	Melbourne Dental School
Host–Microbe interactions; investigating mucosal and systemic immune responses to bacteria	Prof Neil O'Brien-Simpson	Melbourne Dental School
Infiltration of carious lesions with resin	Head of Laboratory Professor David Manton	Melbourne Dental School
Investigating mucosal and systemic immune responses to bacteria	Prof Neil O'Brien-Simpson	Melbourne Dental School
Microbial flow cytometry; developing diagnostic tools for immune responses to bacteria, nano and micro materials and vesicles	Prof Neil O'Brien-Simpson	Melbourne Dental School
Outer membrane vesicles and polymicrobial chronic disease	Prof Stuart Dashper	Melbourne Dental School
Remineralisation of enamel with CPP-ACP and fluoride	Head of Laboratory Professor David Manton	Melbourne Dental School
The development of novel antimicrobial peptides from biological sources	Head of Laboratory Professor Eric Reynolds	Melbourne Dental School
The Oral Microbiology and Microbiome Group	Head of Laboratory Professor Stuart Dashper	Melbourne Dental School
The oral microbiome in health and disease	Dr Catherine Butler	Melbourne Dental School
The physical and optical characteristics of hypomineralised enamel	Head of Laboratory Professor David Manton	Melbourne Dental School
The proteomic analysis of oral bacterial pathogens	Head of Laboratory Professor Eric Reynolds	Melbourne Dental School
The remineralisation of hypomineralised enamel	Head of Laboratory Professor David Manton	Melbourne Dental School
Vaccine design and development to improve immune responses to viral diseases and cancer	Prof Neil O'Brien-Simpson	Melbourne Dental School